Mitochondria are the energy-makers of every cell in the body, including skin cells. During the energy-making process, mitochondrial reactive oxygen species (ROS) are generated. These ROS are able to damage the mitochondria themselves, reducing their energy producing capacity. Without optimal energy, skin cells are unable to regenerate as quickly.

The amino acid ergothioneine is able to enter skin cells and accumulate in the mitochondria, scavenging ROS and protecting them from oxidative damageix. Improved mitochondrial function results in regenerated, more youthful skin.