The LYMA Laser PRO and LYMA Laser are engineered using low level laser therapy (LLLT), also known as photobiomodulation. They deliver near-infrared laser light at 808 nanometers that is monochromatic, coherent and polarized. This cold laser technology operates without generating heat or causing surface damage to the skin. Unlike traditional aesthetic lasers that rely on thermal energy or controlled trauma, LYMA's laser technology delivers light energy at intensities designed to interact with cellular structures without triggering inflammatory responses. The LYMA Laser is a 500mW device with an 8cm² treatment lens, while the LYMA Laser PRO is a 1450mW device with a 30cm² treatment lens, both engineered with patented ultra-diffused lenses that allow for safe at-home use.

SIRT1 (Sirtuin 1) is a protein that plays a recognised role in cellular regulation, including processes linked to metabolism, stress response and longevity. In skin science, SIRT1 is of interest due to its involvement in cellular signaling pathways that influence how skin cells respond to environmental factors over time. It is frequently discussed in academic research focused on aging, regeneration and the biological mechanisms underpinning skin health.

The reference is to a peer-reviewed study published in Aesthetic Medicine Journal in 2025 which explored the interaction between low level laser light and cellular signalling pathways associated with skin biology. The study examined the effects of near infrared, non-thermal laser light within a controlled clinical setting, contributing to the wider body of research into photobiomodulation and its potential relevance to skin science and aging research.

The LYMA Laser uses near-infrared light at 808 nanometers to penetrate deep into the skin, where it is absorbed directly by cellular mitochondria. This process, known as photobiomodulation, triggers biological signaling pathways that upregulate longevity genes, particularly SIRT1. In published clinical research, the LYMA Laser upregulated SIRT1 6-fold, activating genes responsible for cellular repair, DNA protection and collagen production. Unlike traditional lasers that rely on heat or trauma, this cold laser technology energizes cells to function younger without causing any damage or inflammatory response.

In clinical and research environments, laser technologies are regulated according to their intended use, power output and risk classification. In the United States, certain medical and aesthetic laser systems may be reviewed or cleared by the FDA for specific clinical applications. This regulatory framework relates to clinical laser systems, rather than consumer cosmetic devices, and are designed to ensure safety and appropriate use within professional settings.

In the landmark 2025 study published in the Aesthetic Surgery Journal, researchers conducted comprehensive genetic testing to examine how the LYMA Laser affects cellular behavior. Of the 107 genes analyzed - many of which are associated with aging, collagen production, inflammation and cellular stress - 45 showed significant activation or modulation in response to the laser treatment. This demonstrates that the LYMA Laser doesn't just affect the skin's surface, but triggers meaningful biological changes at the genetic level, particularly in genes controlling longevity, repair mechanisms and youth-associated cellular functions.

Longevity science focuses on gradual biological changes that occur over extended periods rather than immediate or short-term shifts. The processes that control aging, such as cellular energy production, gene expression and collagen synthesis, respond to sustained signals over time. This is why consistency is fundamental to the Science of Youth approach. Just as aging happens progressively at the cellular level, reversing or slowing these processes requires regular, ongoing stimulation. The LYMA Laser, Supplement and Skincare are engineered to work cumulatively, with daily use creating sustained biological effects that compound over weeks and months rather than offering temporary cosmetic fixes.

The LYMA Supplement works synergistically with the LYMA Laser and Skincare as part of the complete Youth System. While the Laser activates longevity genes and energises cellular function from the outside, the Supplement supports these same biological processes from within. Formulated with eleven patented ingredients at clinically proven doses, it targets cellular stress, inflammation and metabolic pathways that influence how your body ages. When used together, these technologies create a comprehensive approach to longevity; the Laser regenerates skin cells at the genetic level, the Skincare delivers bioactive compounds to all skin layers, and the Supplement provides internal nutritional support for sustained cellular health and resilience.

The Science of Youth recognizes that aging is a whole-body process influenced by multiple interconnected biological systems. The LYMA Laser activates longevity genes and powers up mitochondria to regenerate collagen and elastin without damage. LYMA Skincare delivers bioactive ingredients that target the eight mechanisms of skin aging across all skin layers, supporting the skin's barrier function and cellular signalling. The LYMA Supplement addresses aging from within, providing patented ingredients that support cellular stress response, metabolism and inflammation pathways. Together, these three technologies create a complete regeneration system, addressing youth at both the cellular and genetic levels, from internal biological processes to external skin health. This integrated approach reflects how longevity science views aging: as a complex, multi-system process that requires comprehensive intervention rather than isolated treatments.

The patented epigenetic skincare actives in the LYMA Serum and Cream and the active stabilized oxygen in the Mist and Glide products, have been specifically formulated to work in conjunction with the low-level laser technology in the Laser PRO.

The Laser PRO delivers the precise near infrared laser power proven to stimulate cellular regeneration and the LYMA Skincare delivers a unique set of actives proven to maximize the power of the LYMA Laser.

However you can use any other skincare with the LYMA Laser and achieve powerful results.

Modern longevity research demonstrates that ageing is not caused by a single factor but by multiple interconnected processes occurring simultaneously. Addressing only one aspect provides limited results. The Science of Youth combines three complementary technologies because each targets different but related mechanisms of ageing. This multi-layered approach mirrors how longevity scientists now understand ageing, as a system-wide process that benefits most from comprehensive, integrated intervention.

All Starter Kit, Systems and Refill orders ship free of charge, and import duties are paid for by LYMA, meaning the price you pay at checkout is the final price of your product. Local sales tax will be added as normal if that applies in your region. Delivery charges for accessories which are not part of an order containing a Refill, System or Starter Kit are shown at checkout. Estimated delivery times are based on business days (Monday to Friday). Orders placed on Saturday or Sunday will be shipped on the next working day (Monday, provided it is not a public holiday). You can track your order in My Account.

Yes. LYMA ships to over 100 countries worldwide with tracked and insured delivery. Shipping times vary by destination, and all taxes and duties are calculated at checkout for a seamless, worry-free gifting experience.

You can see the countries available for shipping during the checkout process.

We are happy to refund or exchange any product returned within 14 days of purchase, if it is returned in its original state, unused and in original packaging with the hygiene seal unbroken.

Please contact concierge@lyma.life to arrange to return your item.

The LYMA Supplement or LYMA Laser are available to purchase with or without a subscription. To place an order, click here.

Experience the full benefits of LYMA by selecting our subscription. Through your account, you can easily start, pause or cancel your subscription, update your delivery address or amend your subscription renewal date.

To start your LYMA journey without a subscription, simply select 'one-off purchase'.

You are able to re-order refills or start a subscription through your account, at any time.

You can check the status of your delivery using the DHL tracking information sent to you once your package is dispatched.

Our dedicated customer support team is available to assist you with any questions or concerns. You can reach us through our Contact Us page, where you'll find multiple ways to get in touch. For immediate assistance with order tracking, product questions or general inquiries, please visit our FAQs page which may provide quick answers to common questions. We're committed to ensuring you have the best possible experience with LYMA and aim to respond to all inquiries promptly.