LYMA Laser on The Human Upgrade - when the world's most rigorous biohacker meets real science.
“When someone with that level of intellectual rigour sits across from you and says this is real - it lands differently.”
Dave Asprey has spent two decades sitting across from the world’s leading longevity scientists, biohackers, and medical pioneers. He has interrogated Nobel laureates, geneticists, and performance researchers on The Human Upgrade - one of the most influential health podcasts in the world. He knows what real science looks like. And he knows how to spot the difference between a breakthrough and a marketing claim.
Which is why it matters that LYMA Laser is the technology he chose to platform. In his latest episode, Dave goes deep on photobiomodulation - and on why LYMA stands apart from everything else in the field. Not as an aesthetic device. Not as a wellness trend. But as a precision instrument backed by published, peer-reviewed science that most of the industry cannot get near.
Together they unpacked everything the myths get wrong about photobiomodulation. That it’s superficial. That lasers are for vanity. That the science is soft. Dave has heard those arguments from every direction - and he’s also spent long enough in the data to know when something genuinely changes the conversation.
The science tells a different story. Cellular regeneration. Mitochondrial function. Gene activation at a level that doesn’t just slow ageing - it redefines what ageing even means. LYMA’s published research in the Aesthetic Surgery Journal documents what happens at a molecular level when coherent, polarised 808nm light meets human dermis: 45 longevity genes activated, including a sixfold increase in SIRT1 - a pathway central to how cells repair, replicate, and survive.
Execution Is Everything
What Dave recognised immediately is what has always driven the obsession behind LYMA Laser: execution is everything. The science of photobiomodulation has existed for decades. What hasn’t existed is a device precise enough, powerful enough, and coherent enough in its delivery to actually honour that science.
Most devices in the ‘red light’ category are, in Dave’s words, glorified LEDs. They can be fine for the surface - but they do not deliver the kind of coherent, polarised, monochromatic light that cells actually respond to in deep tissue. That distinction is not marketing. It is physics. And it matters because your mitochondria run the whole show. When they get a clean signal and more usable energy, the body suddenly has the budget for repair, collagen synthesis, circulation, and recovery.
That is the real mechanism behind anti-ageing that does not rely on controlled injury. No damage. No downtime. No inflammation manufactured in the hope of triggering a healing response. Just signal - precise, coherent, and deeply penetrating.
The Personal Is the Scientific
Dave also brought something we rarely hear articulated with such clarity: that the future of biohacking is not pharmaceutical. Not passive. It is profoundly, beautifully personal. The tools that will define the next chapter of human health are the ones that put biological intelligence back in the hands of the individual.
Your skin is not just a cosmetic surface. It is a living organ that responds to signals. The right light signal can flip your biology into repair mode. It’s not a metaphor. It’s cellular reality - and coming from someone who has interrogated that reality with the world’s foremost scientific minds, it lands with the full weight of that credibility.
When someone with that depth of knowledge, that network of expertise, and that level of intellectual rigour says this is real - it means something. It means the obsession was right. The decade of development was worth it. And the future of human health is exactly what LYMA always believed it would be: not pharmaceutical, not passive, but profoundly, beautifully personal.
WATCH THE EPISODE
