See what the experts say on LYMA Laser technology and LLLT in this peer-reviewed evidence.
The science and further reading
There are thousands of scientific journals published on the subject of Low-Level Laser Therapy (LLLT) and its regenerative and healing properties. See what your peers are saying on LYMA Laser technology and LLLT in just some of the peer-reviewed evidence for near-infrared laser in plastic surgery.
Glass G.E. Photobiomodulation: A review of the molecular evidence for low level light therapy. Journal of Plastic, Reconstructive & Aesthetic Surgery 2021. Read on PubMed
Hode et al. The importance of coherence in phototherapy. Mechanisms for Low-Light Therapy IV 2009. Read the SPIE paper
Karu T. Primary and secondary mechanisms of action of visible to near-IR radiation on cells. Journal of Photochemistry and Photobiology 1998. Read the research
Glass G.E. Photobiomodulation: The Clinical Applications of Low-Level Light Therapy. Oxford University Press. View full text
Mechanistic summaries
Avci et al. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Seminars in Cutaneous Medicine and Surgery, 2013. Read on NIH
da Silva et al. Laser therapy in the tissue repair process: a literature review. Photomedicine and Laser Surgery, 2010. Read journal
Chung et al. The nuts and bolts of low-level laser therapy. Annals of Biomedical Engineering, 2012. Read paper
Avci et al. Low-level laser therapy for treatment of hair loss. Lasers in Surgery and Medicine, 2014. Read more
Houreld N.N. The use of lasers and light sources in skin rejuvenation. Clinics in Dermatology, 2019. View article
Pre-clinical studies
Gupta et al. Effect of red and near-infrared wavelengths on wound healing in mice. Lasers in Medical Science, 2014.
Ma et al. Effect of low-level laser therapy on collagen synthesis in fibroblasts. Journal of Wound Management and Research, 2018. Read the study
Clinical trials
Hopkins et al. LLLT facilitates superficial wound healing: a triple-blind, sham-controlled study. Journal of Athletic Training, 2004. View trial
Kajagar et al. Efficacy of LLLT on wound healing in diabetic foot ulcers. Indian Journal of Surgery, 2012. Read trial
Gupta et al. Low energy photon therapy in venous leg ulcers: a placebo-controlled study. Dermatologic Surgery, 1998. Read study
General reading
Avci et al. Primary and secondary mechanisms of action of visible to near-IR radiation on cells. Semin Cutan Med Surg, 2013. Read full text
Karu T. LLLT in skin: stimulating, healing, restoring. Journal of Photochemistry and Photobiology, 1998. Read journal
Photobiomodulation: A systematic review of the oncologic safety of LLLT for aesthetic skin rejuvenation. Aesthetic Surgery Journal Open Forum, 2023. Read review
