The Science Around the LYMA Laser PRO Technology

See what the experts say on LYMA Laser technology and LLLT in this peer-reviewed evidence.

3 Minute ReadEducation

23.02.24

The science and further reading

There are thousands of scientific journals published on the subject of Low-Level Laser therapy (LLLT) and its regenerative and healing properties. See what your peers are saying on LYMA Laser technology and LLLT in just some of the peer-reviewed evidence for near-infrared laser in plastic surgery.

Glass G.E. Photobiomodulation: A review of the molecular evidence for low level light therapy. Journal of Plastic, Reconstructive & Aesthetic Surgery 2021.

https://pubmed.ncbi.nlm.nih.gov/33436333/

Hode et al. The importance of coherence in phototherapy. Mechanisms for Low-Light Therapy IV 2009.

https://www.spiedigitallibrary.org/conference-proceedings-of-spie/7165/716507/The-importance-of-coherence-in-phototherapy/10.1117/12.809563.short

Karu T. Primary and secondary mechanisms of action of visible to near-IR radiation on cells. Journal of Photochemistry and Photobiology 1998

https://pubmed.ncbi.nlm.nih.gov/10365442/

Glass G.E. Photobiomodulation: The Clinical Applications of Low-Level Light Therapy. Oxford University Press.

https://academic.oup.com/asj/article/41/6/723/6104785

Mechanistic summaries

Avci, P., Gupta, A., Sadasivam, M., Vecchio, D., Pam, Z., Pam, N. and Hamblin, M.R., 2013, March. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. In Seminars in cutaneous medicine and surgery (Vol. 32, No. 1, p. 41). NIH Public Access.

https://www.ncbi

da Silva, J.P., da Silva, M.A., Almeida, A.P.F., Junior, I.L. and Matos, A.P., 2010. Laser therapy in the tissue repair process: a literature review. Photomedicine and laser surgery, 28(1), pp.17-21. https://www.liebertpub.com/doi/full/10.1089/pho.2008.2372

Chung, H., Dai, T., Sharma, S.K., Huang, Y.Y., Carroll, J.D. and Hamblin, M.R., 2012. The nuts and bolts of low-level laser (light) therapy. Annals of biomedical engineering, 40, pp.516-533.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288797/

Avci, P., Gupta, G.K., Clark, J., Wikonkal, N. and Hamblin, M.R., 2014. Low‐level laser (light) therapy (LLLT) for treatment of hair loss. Lasers in surgery and medicine, 46(2), pp.144-151.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944668/

Houreld, N.N., 2019. The use of lasers and light sources in skin rejuvenation. Clinics in dermatology, 37(4), pp.358-364.

https://www.researchgate.net/publication/332840167_The_use_of_lasers_and_light_sources_in_skin_rejuvenation

Pre-clinical studies

Gupta, A., Dai, T. and Hamblin, M.R., 2014. Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice. Lasers in medical science, 29, pp.257-265.

Ma, H., Yang, J.P., Tan, R.K., Lee, H.W. and Han, S.K., 2018. Effect of low-level laser therapy on proliferation and collagen synthesis of human fibroblasts in vitro. Journal of wound management and research, 14(1), pp.1-6.

https://scite.ai/reports/effect-of-low-level-laser-therapy-YaDaJz

Clinical trials

Hopkins, J.T., McLoda, T.A., Seegmiller, J.G. and Baxter, G.D., 2004. Low-level laser therapy facilitates superficial wound healing in humans: a triple-blind, sham-controlled study. Journal of athletic training, 39(3), p.223.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC522143/

Kajagar, B.M., Godhi, A.S., Pandit, A. and Khatri, S., 2012. Efficacy of low level laser therapy on wound healing in patients with chronic diabetic foot ulcers—a randomised control trial. Indian Journal of Surgery, 74, pp.359-363.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477409/

Gupta, A.K., Filonenko, N., Salansky, N. and Sauder, D.N., 1998. The use of low energy photon therapy (LEPT) in venous leg ulcers: a double‐blind, placebo‐controlled study. Dermatologic surgery, 24(12), pp.1383-1386.

https://pubmed.ncbi.nlm.nih.gov/9865208/

General reading

Avci et al. Primary and secondary mechanisms of action of visible to near-IR radiation on cells . Semin Cutan Med Surg 2013.

https://pubmed.ncbi.nlm.nih.gov/10365442/

Karu. Low-Level Laser (light) Therapy (LLLT) in skin: stimulating, healing, restoring. Journal of Photochemistry and Photobiology 1998.

https://www.scmsjournal.com/article/abstract/low-level-laser-light-therapy-lllt-in-skin-stimulating-healing-restoring/

Photobiomodulation: A systematic review of the oncologic safety of Low-Level Light Therapy (LLLT) for aesthetic skin rejuvenation. Aesthetic Surgery Journal Open Forum.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309024/

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