The Truth About Supplements

Dr Paul Clayton PhD, Clinical Pharmacologist
and LYMA Director of Science

For the last fifty years I have been studying the pharmacological effect of foods and food extracts, and how these can be used to reduce your chances of illness and to make you feel and function better.

Dr. Paul Clayton has a PhD in clinical pharmacology, is a former senior scientific advisor to the UK government committee on the Safety of Medicines and works as the Director of Science for LYMA.

What's Wrong With the Supplement Industry?

There are a lot of problems with the supplement industry in its current form. Today's supplement industry is irresponsible, characterised by unstandardised, unproven extracts. The largest sector of the supplement industry, the billion dollar fish oil industry, is a confidence trick. We all know Omegas 3, 6 and 9 are good for us, but there is little evidence that supplementing with fish oil capsules is an effective way to take these nutrients on board. Added to that, the Guardian recently covered an extensive report which found that most fish oil capsules were in fact rancid by the time they reached supermarket shelves. It's a similar story for many multivitamin brands: often the amount of benefit they deliver can easily be delivered as part of a balanced diet. Many deliver little benefit at all. The regulation is extremely poor. Meanwhile what regulation there is inhibits manufacturers of supplements with proven benefits being able to say exactly what their products can do.

More Than a Vitamin Pill?

Other supplements make up for deficiencies; LYMA goes beyond this. Here's how.

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Why Doesn't the Medical World Focus On Preventative Health?

By the time a patient goes to a doctor, it's often too late. Rather like a fire engine arriving at a house long after the house is burnt three-quarters to the ground. By the time medics arrive on the scene, the tools that they have merely treat the symptoms. For years, the pharmaceutical industry has shown no interest in preventative health. Instead, their focus is on treating symptoms, rather than preventing disease occurring in the first place. The bulk of the medical business is not in cure, but in treatment. This is because health services are largely focussed on the treatment of chronic degenerative disease, the diseases that are attacking the health span of the western world. These include diabetes, cancer, osteoarthritis, Alzheimer's and osteoporosis. Doctors tend to come onto the scene to treat these diseases late in the day, as they burn long and slow under the surface in their preclinical phase. Most patients don't realise they are suffering, as it takes a long time for them to reach the point where so much healthy tissue has been destroyed, that the patient notices symptoms of pain or disability.

The Growing Public Health Disaster: What Can We Do?

We are a desperately unhealthy population, which the medical profession is not in a position to address. Focussed on reactive medicine, it is all they can do to firefight the symptoms, when they should be taking a step back to consider the cause. The reason for this is they don't have the right tools to prevent conditions from occurring. Drugs aren't the answer; instead we need to undo the problems that are creating the growing public health disaster. These tools are nutritional. This is where true prevention lies.

"We need to undo the problems that are creating the growing public health disaster. These tools are nutritional. This is where true prevention lies."
By Dr Paul Clayton PhD.
Clinical Pharmacologist and LYMA Director of Science

What Can Be Done to Help Prevent Chronic Degenerative Disease?

Pharmaco-nutritional tools can do far more than pharma-tools, so far as preventative disease is concerned. They act in a far more profound way. They reset the metabolic errors that drive chronic degenerative disease, getting to the heart of the matter in a way that pharmaceutical tools simply cannot do. I think that it's time to bring clarity and rigour to this sector because now that evidence-based nutrition is coming of age, we need to find a way to convey this information in simple, but honest ways, to consumers who can then use it to improve their own health. We need a new regulatory system.

The Supplement Industry Is Misleading. We Need Better Regulation

The supplement industry lacks regulation and ultimately puts consumers at risk. A vast amount of the products in the industry are unproven and the regulatory climate needs to be stricter. Meanwhile, peer-reviewed ingredients aren't allowed to make any medical claims. Contents should match label claims, but these are not rigorously checked, equally watch our for rancid ingredients that have long past their sell by date or are not stable enough to survive manufacture and distribution.

The current regulatory system makes it impossible for the few companies like LYMA who are formulating with validated nutritional ingredients to talk truthfully about what they have. So, the consumer has the worst of all possible worlds as the companies who are in a position to offer solutions are unable to legally talk about it.

The advent of processed food has brought about wide scale dysnutriton. As a society we are eating too much, and much of that is empty calories, not providing us with the nutrition our bodies need. The evidence for the therapeutic effects of nutritonal enhancement from epidemiological research, preclinical models and clinical trials is overwhelming and yet the regulatory system has not yet taken this into account. We desperately need a new regulatory system to look at the real, 21st century science that's being done in this sector, allowing responsible brands to speak about ingredients that have been shown repeatedly in a range of studies to exert benefits. At the moment we have this very odd situation where you have a lot of companies in the supplement sector who clearly, when you look at what they're selling, have no idea about what it is that they are selling, and consumers who are completely misinformed, and who don't know what they're buying. You wouldn't want to run a railroad or any other kind of industry on this basis.

Your Questions Answered, By Dr Paul Clayton PhD

What to look for when selecting an effective supplement?

A lot of supplements are formed by companies who don't know and don't care what they're putting in their products. They can get away with this as consumers don't understand what they are buying. It's a shame, because the potential benefits of well-designed nutrition are real and very significant.

If you are interested in improved functionality, then choose the supplements like LYMA, which use genuinely validated extracts. These are extracts that have been intensively researched, and carefully sourced. This makes them expensive so it beholds the company involved to patent their extracts. Look for products which contain trademarked compounds, where there is peer-reviewed literature behind them that proves their preclinical and clinical functionality. Go for transparency.

What does a peer-reviewed ingredient actually mean?

Peer-reviewed ingredients are shown in preclinical and clinical trials to work. These are patented compounds or extracts which are backed by considerable financial investment and characterise molecules in a way no one else has done before. This category of nutrition is moving the framework of the supplement debate wider, providing assurance of demonstrable effects over and above standard nutrition.

Every brand says 'clinically tested' but what level of clinical research should I be looking for?

Not all clinical trials are to be trusted. Just as you wouldn't trust a medicine that hasn't been peer-reviewed, so you shouldn't trust a supplement that hasn't been peer-reviewed either. Due to the fact the industry isn't regulated, any brand can pay for a private clinical study, doctor the results and state any outcome. However, peer-reviewed studies have been reviewed and approved by an independent team of experts, published in medical journals and therefore can be fully trusted. Choose a supplement which includes ten peer-reviewed ingredients and offers the highest level of transparency and efficacy.

Is it best to go for all-natural organic supplements?

You have to look at each ingredient on an individual basis. There are people who swear that everything has to be all natural all of the time. The reality is you can be a little more granular. There are some nutrients, such as vitamin C, where it really doesn't matter whether what you're taking is vitamin C cherry extract or a synthetic form, because the molecule is so simple that it's identical. There are some of the molecules which have what they call stereoisomerism; in other words, molecules which are either right or left-handed. They look the same, but they're not. This is true in the forms of vitamin E, where I would recommend using the natural rather than synthetic form. I'm afraid you have to be specific and look at these item by item.

Also, when it comes to plant or herb extracts, organic isn't always a benchmark for efficacy. Organic doesn't assure you that the extract won't be killed off by the acid in your stomach, or be bioavailable, or stable. In many instances, organic supplements have to be adapted in order to provide benefits once ingested.

What makes LYMA stand out in the market?

LYMA sets the standard for the next generation of evidence-based nutrition. LYMA isn't a supplement, at least not in the old-fashioned sense. The key aspect of LYMA that I believe is a step in the right direction, is that it exclusively uses actives which have been validated. These aren't your standard run of the mill vitamins and minerals. These are food or herbal extracts which have been shown in peer-reviewed studies to have a specific effect. For the first time you have a generation of products, which do what they say on the can. Which have a substantial body of evidence behind them and set the standard for the next generation. This is evidence-based nutrition.

Three steps to check if your supplements are likely to work

When you are choosing a supplement, this is LYMA's recommended label checklist:

1. Check for patented ingredients. Do you see a TM or R next to a single ingredient on the ingredient label to see if the ingredient is patented? If you don't see a TM or R next to the single ingredient, it means the ingredient is generic and likely unproven.

2. Check for evidence. If you do see a patented ingredient, go to www.pubmed.gov. Type the branded ingredient in the search bar and look to see if the exact brand of ingredient has been published in a peer-reviewed medical journal. For example, if you are searching for Wellmune Blend®, don't search for beta glucans (its generic form), search for Wellmune Blend®.

3. Check for levels. Now confirm that the dosage level in your supplement matches the dosage level in the peer-reviewed study. If it's not dosed correctly, you can't be sure it will provide the same benefits.

If both the ingredient and the dosage level have been featured in a study on Pubmed, you can trust the ingredient will work.

What the experts say

Ten Proven Ingredients.
One Perfect Formula

Ultimate bioavailability, optimised dosage, high-tech delivery system.

Industry Reviews

Kate Kerr

"LYMA is the most advanced supplement I have tried to date. I can honestly say that it’s, without question, the most effective supplement that I’ve taken."

Kate Kerr, Acclaimed Clinical Facialist

Dr Keira Barr

"Using LYMA simplified my daily supplement regime."

Dr Keira Barr, Dual board-certified Dermatologist and Menopause Specialist

Dr Nina Bal, BDS

"Since starting to take LYMA daily, I have noticed dramatically improved skin and it has helped my hair to grow back thicker and stronger than ever following both of my pregnancies."

Dr Nina Bal, BDS, Cosmetic Dental Surgeon and Facial Aesthetics Doctor

Dana James MS, CNS, CDN

"With LYMA, there's nothing that's superfluous, it's a synergistic product that works on many biochemical levels. It helps with sleep, anxiety, mood, skin and bones."

Dana James MS, CNS, CDN, Triple certified Nutritionist, Functional Medicine Practitioner and Cogitative Behavioural Therapist

Dr Adrian Lopresti PhD

"LYMA contains an impressive combination of high-quality, research-driven, patented ingredients that can help people."

Dr Adrian Lopresti PhD, Clinical Psychologist and Researcher

Dr Michael A. Grandner, PhD, MTR

"Each ingredient has been tested, vetted and demonstrated its worth in a clinical trial and most importantly, at the dose that’s in there."

Dr Michael A. Grandner, PhD, MTR, Director of the Sleep and Health Research Program at the University of Arizona, and Director of the Behavioural at the Banner-University Medical Centre

Diane Nivern

"Taking the formula daily has helped me stay focused, energised yet calm, whilst also giving my hair, skin and nails and real boost!"

Diane Nivern, Award winning skincare specialist & facialist

Heather Jackson

"GenM completely supports and applauds the ethos, vision and purpose of LYMA and its founder, Lucy Goff."

Heather Jackson, Co-Founder of GEN M, a digital platform helping women thrive during the Menopause

Dr Donald Cox PhD

"The best way to protect yourself is to take a product like Wellmune® Blend, which is a component of the LYMA supplement, to enhance your immune system."

Dr Donald Cox PhD, Food Microbiologist at Cornell University

Customer Reviews

4.5 Stars

From 197 people

Larita
USA
4 days ago

I felt good when I was on it for a few months. I didn’t feel any anxiety and it seems to be creeping up on me so I want to try it for longer to see if it can keep any anxiety from coming back.

Melanie
Canada
4 days ago

My husband and I have been taking LYMA for two years. We absolutely love it!

Emma
UK
1 month ago

I have noticed a profound difference in the quality of my sleep and I'm waking up less during the night.

Sarah
UK
2 months ago

I love the supplements. They have made a noticeable difference for me. I am sleeping better. My stomach feels very settled - I have been suffering with a stomach ulcer for approx. 18 months. I have stopped taking any medication for that since I started taking the LYMA supplements. Altogether I feel generally very very well!!

Alison
UK
2 months ago

Loving my Lyma journey and I recommend to everyone of my girlfriends.

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