Discover the health benefits of LYMA's new wonder-ingredient affron®



The world’s best supplement just got even better. As science evolves, so too does LYMA. We are over the moon to introduce a brand new ingredient to our unique formula; a new ingredient that promises to deliver increased resilience against chronic inflammaging, boost mood and further improve sleep quality.

We know that pharmaco-nutrition evolves rapidly, meaning LYMA is in a constant development phase. We are always on the lookout for innovation, and continually adapt and enhance our formula to ensure we remain the best and most effective on the market. From this month LYMA subscribers will benefit from the addition of affron®, a totally unique and highly concentrated standardised saffron extract, as well as an increased 600mg daily dose of our powerful anti-inflammatory turmeric extract, HydroCurc®. LYMA is now the only supplement in the world to feature nine peer-reviewed, patented ingredients, each dosed at active, clinically proven, levels.

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Saffron is the most expensive spice in the world, and for good reason - it is both incredibly labour intensive to extract and has extremely potent health properties. Saffron itself is well-known for its mood-boosting properties and affron® is the first saffron supplement on the market to be supported and backed by clinical evidence. To date, six peer-reviewed studies have demonstrated the positive effect that affron® has on mood and sleep quality in healthy adults. Furthemore, affron® is effective when taken alongside prescription antidepressants in order to reduce their side effects. So what is affron®? What makes affron® so special? And how could affron® boost your health and wellbeing?

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1. Improved mood

affron® can be effective in reducing depression in adults with persistent depressive symptoms. Peer-reviewed evidence has demonstrated its effectiveness at a daily dose of 28mg in alleviating low mood states and anxiety by enhancing resilience and our ability to deal with adversity.

Emotional resilience is dependent on specific genes and ion channels in the ventral tegmental area (VTA) of the brain. affron® works directly to alter these genes, ion channels and neurons, increasing emotional resilience and improving mood.

affron® is clinically proven to help maintain a positive mood, manage anxiety and promote restorative sleep. Regular supplementation with affron® has been shown to increase the benefits associated with antidepressant medication when taken alongside pharmaceutical antidepressants, and has been implicated in mitigating side effects often associated with antidepressant usage.

Supplementing with affron® has been linked to a reduction in the amount of the stress hormone cortisol circulating in the bloodstream, and some studies even suggest that it can be just as effective as pharmaceuticals for treating depression.

The active doses of Wellmune® and KSM-66® Ashwagandha in the LYMA formula play powerful roles in mood augmentation too.

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2. Anti-inflammatory and antioxidant properties

affron® contains a number of anti-inflammatory and antioxidant plant compounds that can protect your body and its cells against free radical damage and oxidative stress. This can be a particular problem as one gets older and inflammaging begins to take hold. The specific antioxidants present in affron® are crocin, crocetin, safranal, and kaempferol.

Crocin and crocetin are the carotenoids that are responsible for affron®’s antidepressant properties. They also help to protect your brain cells and neural networks from the effects of oxidative stress, and contribute to improved complexion and a reduction in appearance of fine lines and wrinkles as you age.

Safranal is the antioxidant that you can taste when you eat saffron; it is also the compound responsible for supporting memory, focus and attention and the reason that saffron is often associated with improved brain health and cognitive function.

Kaempferol is a powerful antioxidant that is also present in affron®. Antioxidants are known to neutralise the harmful free radicals that can contribute to all manner of illnesses, disease and health problems, including cancer. Kaempferol has been linked with the prevention of certain types of cancer and, in particular, colon cancer.

Furthermore, it has been suggested that crocin (one of the carotenoids present in affron® that has been linked to reducing depression) may increase the sensitivity of cancer cells to chemotherapy drugs, making treatment more effective.

LYMA also contains anti-inflammatory HydroCurc®, a 100% bioavailable curcumin designed for cellular protection and inflammation reduction, at a clinical dose of 600mg and Lycored Lycopene™, the best antioxidant to protect against the ravages of urban life, at a scientifically proven dose of 30mg

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3. Hormone balancing

affron® can be a really useful addition to your hormone-balancing regime, particularly if your hormones are already out of whack and you suffer with premenstrual syndrome (PMS) and dread the associated physical, emotional, and psychological rollercoaster that happens each and every month.

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A study that looked into the epidemiology of premenstrual syndrome in women aged 20 to 45 found that supplementing with saffron has a positive effect on relieving PMS symptoms when compared with a placebo. A second study found that merely smelling saffron might help reduce PMS symptoms, although not to the same degree as taking it in supplement form.

Saffron has long been used to treat PMS symptoms, and affron® may just be the key to unlocking hormonal balance. LYMA’s 600mg of adaptogen KSM-66® Ashwagandha also plays a pivotal role in restoring the body to physical, mental and hormonal balance.

The new and improved LYMA formula has been created to boost beauty and brains, lift your mood, reduce inflammation and support your immune system. With the recent addition of affron® to our formula, LYMA is better placed than ever before to help you look great, feel incredible and unlock your potential. Because we know that when you feel your best, you can do and be more.

Originally published Sep 8, 2020.


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